PVP VA 64 Copolymer And Copovidone

PVP VA 64 Copolymer And Copovidone

CAS No.: 25086-89-9
Type: Soluble binder, dry binder, film former for granulation
Grade Standard: Cosmetic grade, pharmaceutical grade, industrial grade
Type: Auxiliary agent and other pharmaceutical chemicals
Description: Copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA)
Packaging: 20KG or 25KG cardboard drum or PP drum

Product Introduction

Hangzhou Rainbow Import & Export Co., Ltd. is a reliable supplier of pvp va 64 copolymer and copovidone in China, providing professional sales and export services to global customers. As a sales partner of Huzhou Sunflower Pharmaceutical Co., Ltd., an experienced manufacturer of pvp va 64 copolymer and copovidone, we connect buyers with qualified manufacturers and suppliers and support customized product requirements. Our manufacturing partner's factory provides production support for customer orders. For product specifications, customized solutions, or free sample inquiries, please feel free to contact us.

 

CAS No.: 25086-89-9
Type: Soluble binder, dry binder, film former for granulation
Grade Standard: Cosmetic grade, pharmaceutical grade, industrial grade
Type: Auxiliary agent and other pharmaceutical chemicals
Description: Copolymer of vinylpyrrolidone (VP) and vinyl acetate (VA)
Packaging: 20KG or 25KG cardboard drum or PP drum

 

Characteristics

 

  • Solubilization and Bioavailability Improvement: With good solubilization ability, PVP VA 64 can significantly improve the solubility of the drug in water by forming a complex with the active ingredient of the drug, thus improving its bioavailability.
  • Binder Function: As a binder for solid drugs such as tablets and capsules. Its excellent adhesive effect enables it to enhance the bonding force between particles, thereby improving the mechanical strength and compression resistance of pharmaceutical tablets.
  • Film-forming Properties: Good film-forming properties, able to form transparent, uniform and tough films. This property makes it widely used in drug coatings to protect drugs from environmental factors.
  • Low Toxicity and Safety: It is well metabolized in the human body, has low toxicity, and is suitable for use in a variety of pharmaceutical preparations.

 

Specification

 

  Powder Aqueous Solutions  
SUNVIDONE VA 64P 64W 73W
VP/VA ratio 60/40 60/40 70/30
K value 26-34 26-34 24-32
solids 95%min 48-52% 48-52%
Water 5.0%max / /
Alcohols 0.5%max 0.5%max 0.5%max
Color (APHA)10% 60max 60max 60max
PH (10% solution) 4.0-7.0 4.0-7.0 5.0-6.5
NVP 0.01%max 0.01%max 0.01%max
Vac 0.03%max 0.03%max 0.03%max

 

Application

 

Pharmaceutical Field:

  • Tablets and Capsules: As a binder and film-forming agent, it enhances the structure and stability of the drug and ensures rapid disintegration and release.
  • Oral Sustained-release Preparations: In controlled-release and sustained-release preparations, the drug release time is controlled to extend the drug effect.
  • Solubilizer: Excellent solubilization effect, by forming complexes with these pharmaceutical active ingredients, their solubility and bioavailability can be significantly improved.
  • Drug Coating: It can be used as drug coating material to help improve the appearance and taste of drugs and extend the shelf life of drugs.

 

Cosmetic Field:

  • Hair Styling Products: As a film former, it provides good styling effect and prevents hair from losing its shape in a humid environment.

 

FAQ

 

1.Can PVP VA 64 copolymer be used in sustained-release preparations?
It is often used in sustained-release or controlled-release drug preparations. Its film-forming properties can help control the release rate of the drug, allowing the drug to be released gradually in the body.

 

2. What is the effect of PVP VA 64 copolymer on tablet disintegration properties?
It can play a good disintegration role in tablets, which helps the rapid release of drugs in the gastrointestinal tract.

 

3. Is there a dosage limit for the use of PVP VA 64 copolymer?
In drug preparations, the dosage is usually controlled according to specific drug needs and formulation standards.

 

4. How to store PVP VA 64 copolymer?
It should be stored in a dry and cool environment, avoiding exposure to high temperature or humid conditions.

 

5. Is PVP VA 64 copolymer suitable for patients with allergies?
It usually does not cause allergic reactions, but for a very small number of patients who are allergic to PVP or vinyl acetate, it may cause mild discomfort.

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