What Is Povidone?

Povidone is a water-soluble synthetic polymer whose main component is N-vinylpyrrolidone. It is a polymer with high adhesiveness, mainly used as a binder for wet granulation of solid preparations. Its unique properties make it an extremely important excipient in various oral liquid formulations, suspensions, and topical drug development applications.

Scope of application

Povidone has the properties of binding, thickening, dispersing, film-forming and complexing, so it can be used as a binder for granules and tablets, as a thickener, and suspending agent for liquid preparations. Solubilizers and stabilizers for injections, film-forming agents and pigment dispersants for coating, co-precipitants for poorly soluble drugs, delaying agents and lubricants for ophthalmic drugs, sustained-release agents for controlled-release dosage forms, etc. Precautions

l. This product has strong hygroscopicity. It should be stored in a cool and dry environment and should be sealed after use. For accurate measurement, moisture should be measured before use.

2. If the aqueous solution of this product is not sterilized, it may be contaminated by microorganisms. If you want to store it for a long time. Bacteriostatic agents such as sodium benzoate, potassium sorbate, and sodium propionate should be added as appropriate.

3. For PVP used after the expiration date, the K value should be re-measured before use. for the correct selection.

4. This product can form molecular complexes with drugs with active hydrogen atoms such as sulfathiazole, salicylic acid, phenobarbital, tannin, chloramphenicol, etc., which can change the physical and chemical properties of the original drug. should be considered.