Hangzhou Rainbow Import & Export Co., Ltd. is one of the leading manufacturers and suppliers of crosslinked polyvinylpyrrolidone in China. With abundant experience, we warmly welcome you to buy customized crosslinked polyvinylpyrrolidone from our factory. If you have any enquiry about free sample, please feel free to email us.

Chemical name: Insoluble Polyvinylpyrrolidone product-1-1
USP/EP name: Crospovidone
Synonyms: Crospovidonum; crosslinked PVP
INCCTFA name: Insoluble PVP
Grade: Food grade
CAS NO.25249-54-1
Molecular formula: (C₆H₉NO)n
Trade name: Sunvidone CL

Characteristics

SUNVIDONE CL series are supplied as fine white or almost white powders.
They have a slight characteristic odour and are practically tasteless.
They are insoluble in all the usual solvents.

Specification

Identification	Type A	Type B
Particle size,sieving	15%min.	15%max.
residue fraction
(63microns sieve)
Water,%max.	5	5
Sulphate ash,%max	0.1	0.1
Water-soluble substances,%max.	1.5	1.5
Heavy metals,ppm max.	10	10
Vinylpyrroldione,ppm max	10	10
Peroxides(as H₂O₂),ppm max.	400	1000
Nitrogen,%	11.0-12.8	11.0-12.8

Application

Acts as a super disintegrant in tablets and capsules, promoting rapid disintegration and improving drug dissolution and bioavailability.
Provides excellent formulation compatibility with most APIs and pharmaceutical excipients without negative interactions.
Enhances tablet quality by improving hardness and reducing friability during production and transportation.
Suitable for various solid preparations including immediate-release tablets, chewable tablets and effervescent tablets.

FAQ

1.What is the mechanism of action of cross-linked polyvinylpyrrolidone?
It is mainly reflected in its ability to adsorb impurities and undesirable substances in liquids through its cross-linked molecular structure. Since the cross-linked structure enhances the adsorption performance of PVP, it can effectively remove impure substances in drug preparations and improve the stability of drugs.

2. How is cross-linked polyvinylpyrrolidone used in drug release systems?
It can be used as a drug carrier to control the dissolution rate of drugs. In drug preparations, cross-linked PVP can adjust the release rate of drugs by changing its degree of cross-linking, so that the drugs are released evenly in the body, reduce peak concentrations, improve therapeutic effects, and reduce side effects.

3. Is cross-linked PVP safe for the environment?
The application of cross-linked polyvinylpyrrolidone in the food, pharmaceutical and cosmetic industries has undergone rigorous safety assessments. It is considered safe and harmless to the human body at the recommended dosage.

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Crosslinked Polyvinylpyrrolidone