Hangzhou Rainbow Import & Export Co., Ltd. is a reliable supplier of povidone k series pharmaceutical excipients in China, providing professional sales and export services to global customers. As a sales partner of Huzhou Sunflower Pharmaceutical Co., Ltd., an experienced manufacturer of povidone k series pharmaceutical excipients, we connect buyers with qualified manufacturers and suppliers and support customized product requirements. Our manufacturing partner's factory provides production support for customer orders. For product specifications, customized solutions, or free sample inquiries, please feel free to contact us.

Huzhou Sunflower Pharmaceutical Co. Ltd : Your Trustworthy Povidone K Series Pharmaceutical Excipients Supplier!

Huzhou Sunflower Pharmaceutical Co. Ltd. focus on the development and producing of pharmaceutical excipients and API's. Led by Mr. Wu Jiaxiang, the main PVP founder in China, the team possessed tens of concerned process and application techniques, gathered 35 years of experience of sustainable R&D, engineering practice and marketing, specially in Polyvinylpyrrolidone series (Povidone, Crosspovidone, Copovidone and Povidone iodinated), Chondroitine Sulfate Sodium series and artificial cultivating of Cordyceps. The company is well known as full range covering, high quality and good service in the industry. The company is widely praised by the customer both at home and abroad.

Our Advantages

Products Widely Used

Our company produces NVP Homopolymer, NVP Copolymer, NVP Crosslinked Polymer, PVP Complex Compound and so on, which are widely used in the field of industry, pharmaceutical, cosmetics.

Strong Production Capability

Our company has the GMP production lines of 600 tons annually of Povidone at low molecular weight ( Povidone K12, K15, K17, K25 and K30), 800 tons annually of Povidone at high molecular weight ( Povidone K60, K90, K120), 300 tons annually of Povidone Iodinated with high stability and 100tons annually of Chondroitine Sulfated Sodium.

Quality Guaranteed

Our company has passed ISO quality certification system. Our company has obtained certificates such as ISO9001:2008, MF032698. All products are strictly tested in accordance with industry standards and contract agreements before leaving the factory.

Rich Products

Our company has rich products, such as Polyvinylpyrrolidone series (Povidone, Crosspovidone, Copovidone and Povidone iodinated), Chondroitine Sulfate Sodium series and artificial cultivating of Cordyceps.

PVP K30 Solution

It is a kind of anti-dyetransfer agent. It includes NVP polymer, surfactants, water. Its characters are clear yellowish liquid, soluble in water. It is used as anti-dyetransfer agent in detergents for textile printing, dyeing and washing, improving the whiteness and brightness.

High Quality PVP

Polyvinylpyrrolidone is a polymer with different molecular weight of ethylene pyrrolidone. It is easily soluble in water and will not be electrolyzed. Its aqueous solution can be miscible with the solution of cellulose series. It can also be mixed with non-ionic, anionic or cationic components such as salicylic acid. These products could make the settlement by adding a lot of salt, including K90 easier than K17 settlement. PVP in the difference in different solubility in organic solvents, the following table contains a series of organic solvents.

Coating Prduction; Stomach Soluble Coating Meterial; Tablet For Parmaceutical Production

Stomach Soluble Coating Meterial starts with a waterproof coating with shellac in a coating pan, followed by several coats with the enteric-coated material. In some instances, a sugar coat is applied over the enteric coating. Materials that are used in enteric coating include shellac, cellulose acetate phthalate (CAP), cellulose acetate butyrate, lipids (mixture of myristic acid, hydrogenated castor oil, castor oil, cholesterol, and sodium taurocholate), hydroxy propyl methyl cellulose succinate, and methacrylic acid co-polymers.

Water Soluble Dispersant

Its external properties are Colorless transparent or pale yellow liquid with a slight characteristic odor. Its main properties are non-ionic water-soluble polymer materials, non-toxic, non-Irritant, no VOC and APEO, meet the requirements of the European Union Oeko-Tex 100. And Water Soluble Dispersant is mutually soluble with water and some alcohol-based solvents. With super good frost resistance high temperature resistant performance (minus 20 ℃ -- 70 ℃).

Polyvinylpyrrolidone/Povidone/PVP K Series

Polyvinylpyrrolidone K Serise are excellent new pharmaceutical excipients. They are mainly used as binder for tablets, pills, granules, cosolvents for injections, glidants for capsules, dispersants for liquid preparations and colorants, enzymes and Heat-sensitive drug stabilizer, insoluble drug co-precipitation agent, ophthalmic detoxification agents and lubricants; use of PVP products for excipients have hundreds of drugs.

Multi-Purpose Polymer Polyvinylpyrrolidone (PVP) K Series 9003-39-8 Homopolymer From N-Vinylpyrrolidone

These products are mainly used as film formers, but also as thickeners. The molecular weight determines the setting and adhesive properties of PVP polymers; the higher the molecular weight, the greater the setting. They are ideal for use in water-based applications where a high degree of clarity is required in the finished product (e.g. Gels). For hair-styling applications K30 and K85 are the best of the various molecular weights.

Polyvinylpyrrolidone/Povidone K Series Povidone Powder

Povidone K Series Povidone Powder is white or creamy white powder, odourless, nontoxic, non-irritant, dissolves readily in water,alcohol,amine and many other organic solvents.This kind of powder is widely used in pharmaceutical fields,thanks to it's excellent solubility,film-formingcapability, chemical stability,physiologicalinertia and cementability.

Povidone K Series Pharmaceutical Excipients With Many Uses

Povidone K Series Pharmaceutical Excipients are white free flouring hygroscopic powder, freely soluble in ethanol, methanol, slightly soluble in acetone. Because of its solubility in water and in many organic solvents, its high binding power and ability to form complexes, soluble. Polyvinylpyrrolidone occupies a special position among the synthetic colloids.

Anti-Dyetransfer Agent PVP K30 Solution

Anti-Dyetransfer Agent PVP K30 Solution is a hygroscopic, amorphous polymer supplied as a white, free-flowing powder. It can be plasticized with water and most common organic plasticizers. It is considered to be physiologically inert. This product is cross-linkable to a water insoluble, swellable material either in the course of vinylpyrrolidone polymerization, by addition of an appropriate multifunctional comonomer or by post-reaction, typically through hydrogen abstraction chemistry. PVP products are recommended for dishwashing, fabric care, household cleaning, and industrial and institutional cleaning applications.

Introduction to Povidone K Series Pharmaceutical Excipients

Povidone K series pharmaceutical excipients have been widely applied in medicine and is one of the three new pharmaceutical excipients advocated internationally, among which the most widely used as adhesives for tablets and granules. Povidone K Series can also be utilized as flow aid for capsules, detoxifying agent and lubricant for ophthalmic drugs, a solvent for injection, a dispersant for liquid preparations, and stabilizing agent for enzymes and heat-sensitive drugs. It can also be combined with iodine to synthesize PVP-I disinfectant. Povidone K Series can also be used as a cryopreservation agent in medicine. Hundreds of drugs applied Povidone K Series products as their excipients.

Advantages of Povidone K Series Pharmaceutical Excipients

Versatility

It is used on the skin to treat or prevent skin infection in minor cuts, scrapes, or burns. It is also used in a medical setting to help prevent infection and promote healing in skin wounds, pressure sores, or surgical incisions. Some forms of povidone iodine topical are used inside the mouth to provide temporary relief of minor mouth pain or irritation, sore throat, or canker sore pain. It may also be used for purposes not listed in this medication guide.

Stability

Povidone K Series is not prone to have chemical reaction. Under normal storage conditions, dry Povidone K Series is quite stable. Povidone K Series has excellent physical inertia and biocompatibility and has not stimulation to skin, eyes no stimulation with no allergic reactions and being non-toxic.

Elastic Film

The film it formed in the hair is elastic and shiny, and has excellent carding property as well as being free of dust. Adopting different category of resin can meet various kinds of relative humidity climatic conditions. It is an important raw material of cosmetics, mainly used for hair retaining agent. Therefore, it is an indispensable raw material in styling hair cream, hair gel, and mousse.

Operations You Can Do with a Povidone K Series Pharmaceutical Excipients

Povidone K Series Pharmaceutical Excipients is available in many different forms, such as a liquid, ointment, aerosol powder, cream, spray, swab, and soap. Read and carefully follow any Instructions for Use provided with your medicine. Ask your doctor or pharmacist if you do not understand these instructions.

Povidone K Series Used On The Skin
First clean the area to be treated. Povidone K Series Pharmaceutical Excipients is usually applied to the skin as needed.
Shake Povidone K Series Pharmaceutical Excipients spray well just before each use.
Allow the medicine to dry completely on the skin before applying a bandage. Do not apply a tight bandage.
Do not use this medicine on deep wounds, puncture wounds, animal bites, or serious burns. Do not apply over large skin areas. Each Povidone K Series Pharmaceutical Excipients swab is for one use only.
Do not use Povidone K Series in the mouth if you are using a form that is made for use only on the skin.
If you are using Povidone K Series Pharmaceutical Excipients on your skin, seek medical advice if you have new or worsening symptoms of pain, redness, swelling, rash, or fever.

Povidone K Series Used In The Mouth
When treating an infection, you may be given antibiotic medication to take by mouth. Use all medicines for the full prescribed length of time, even if your symptoms quickly improve.
Povidone K Series used in the mouth may be used up to 4 times per day. How often you can use this medicine depends on what form you use. Follow all directions on the medicine label.
To use Povidone K Series Pharmaceutical Excipients spray in the mouth, spray directly into the mouth or throat. Leave the medicine in place for 15 seconds, then spit it out. Avoid swallowing the spray. Use once every 2 hours as needed.
To use Povidone K Series Pharmaceutical Excipients as a mouth rinse, gargle or swish the liquid for 30 seconds, then spit it out. Do not swallow the liquid. Use up to 4 times per day.
You should not use Povidone K Series Pharmaceutical Excipients for longer than 7 days without medical advice.

Other Important Information Of Usage
Always follow directions on the medicine label about using this medicine on a child. Some forms of povidone iodine topical should not be used in children of certain ages.

Povidone K Series Pharmaceutical Excipients can stain skin, teeth, and fabric. You may use rubbing alcohol to remove staining from your skin. Avoid getting alcohol onto a wound or irritated skin. Stains on fabric can be removed by rinsing with ammonia diluted with water. Avoid getting the medicine on jewelry, especially silver.
Povidone K Series Pharmaceutical Excipients spray is flammable. Do not use near high heat or open flame. Do not smoke until the gel has completely dried on your skin.

What are the Working Theory of Povidone K Series Pharmaceutical Excipients

Povidone K Series Pharmaceutical Excipients is called iodophore which means povidone acts as a carrier of iodine. Iodine is considered as the active moiety that mediates microbicidal actions. When released from the complex, free iodine (I2) penetrates the cell wall of microorganisms quickly, and the lethal effects are believed to result from disruption of protein and nucleic acid structure and synthesis. While the full mechanism of action is not fully elucidated, iodine is thought to inhibit vital bacterial cellular mechanisms and structures, and oxidizes nucleotides fatty or amino acids in bacterial cell membranes 1. Additionally, free iodine disrupts the function of the cytosolic enzymes involved in the respiratory chain, causing them to become denatured and deactivated 1. In vitro evidence suggests that iodine also counteracts inflammation elicited by both pathogens and the host response via multifactorial effects. In hosts, povidone-iodine was demonstrated to modulate the redox potential, inhibit the release of inflammatory mediators such as TNF-α and β-galactosidase, inhibit metalloproteinase production, and potentiate the healing signals from pro-inflammatory cytokines by activation of monocytes, T-lymphocytes, and macrophages, in vitro 1.

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Ultimate FAQ Guide to Povidone K Series Pharmaceutical Excipients

Q: What are side effects of Povidone K Series Pharmaceutical Excipients?

A: Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
This medicine may cause serious side effects. Stop using this medicine and call your doctor at once if you have:
Swelling, pain, warmth, redness, oozing, or other signs of infection; blistering or crusting; or severe irritation, itching, or burning.

Q: What do I need to tell my doctor BEFORE I take this Povidone K Series Pharmaceutical Excipients?

A: Whether you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had.
Whether you are pregnant or may be pregnant. Some forms of this drug are not for use during pregnancy.
Whether you are breast-feeding or plan to breast-feed.
All skin products:
Whether you have an animal bite or a deep puncture wound.
Whether you have a very bad burn or cut.
Whether a large area needs to be treated.
All vaginal products:
Whether you have signs of pelvic inflammatory disease (PID) like belly pain, nausea, throwing up, fever, chills, sores on your genitals, or bad-smelling discharge.
Whether you have just been exposed to a sexually transmitted disease (STD).
Whether you have signs of an STD like more vaginal discharge than normal, change in color of vaginal discharge, or bad-smelling discharge; pain when passing urine; passing urine more often; or sores or ulcers on your genitals.
Throat gargle:
Whether you have thyroid disease.
Whether you are using hydrogen peroxide as a gargle.

Q: How is this Povidone K Series best taken?

A: Used on the skin
Use this drug as ordered by your doctor. Read all information given to you. Follow all instructions closely.
Do not take this drug by mouth. Use on your skin only. Keep out of your mouth and eyes (may burn).
Wash your hands before and after use. If your hand is the treated area, do not wash your hand after use.
It may be covered with a bandage or dressing.

Q: Used for Throat gargle:

A: Gargle the solution in your mouth for 30 seconds and then spit out. Do not swallow.
Measure liquid doses carefully. Use the measuring device that comes with this drug. If there is none, ask the pharmacist for a device to measure this drug.
Do not get this drug in the eyes.
If this drug gets in the eyes, rinse with a lot of water. If eye irritation lasts for a while, talk with the doctor.
Do not let this drug come into contact with jewelry, especially silver.

Q: What do I do if I miss a dose of Povidone K Series?

A: Use a missed dose as soon as you think about it. If it is close to the time for your next dose, skip the missed dose and go back to your normal time. Do not use 2 doses at the same time or extra doses.

Q: How do I store and/or throw out this Povidone K Series?

A: Store at room temperature. Do not freeze.
Protect from heat.
Keep all drugs in a safe place. Keep all drugs out of the reach of children and pets.
Throw away unused or expired drugs. Do not flush down a toilet or pour down a drain unless you are told to do so. Check with your pharmacist if you have questions about the best way to throw out drugs. There may be drug take-back programs in your area.

Q: What is the Production method of Povidone K Series?

A: Its crude product comes from the polymerization of vinylpyrrolidone under basic catalyst or the existence of N, N'-divinyl amidine and further cross-inking reaction. Then use water, 5% acetic acid and 50% ethanol for reflux to until extract ≤50mg/kg (for over 3h).
The 30% to 60% aqueous solution of the purified 1-vinyl-2-pyrrolidone, in the presence of ammonia or amines and also with hydrogen peroxide as the catalyst, has cross-linking and homo-polymerization reaction at a temperature of 50 °C and subject to further purification to obtain the final product.

Q: What is the Chemical Properties of Povidone K Series?

A: Povidone occurs as a fine, white to creamy-white colored, odorless or almost odorless, hygroscopic powder. Povidones with K-values equal to or lower than 30 are manufactured by spray-drying and occur as spheres. Povidone K-90 and higher K-value povidones are manufactured by drum drying and occur as plates.

Q: What is povidone K series used as?

A: Clarifying agent; pigment stabilizer; colloidal stabilizer; It is mainly used for beer clarifying and quality stabilizing, and can also be applied in combination with enzymes and protein adsorbents. It is also used to clarify the wine and as a stabilizer to prevent discoloration.
Used as the fixing liquid for gas chromatography.
It is used as a colloidal stabilizer and clarifying agent for beer clarification. Apply proper amount according the demands of production.
It can be used for pharmacy, aquaculture, and livestock disinfectant for the sterilization of the skin and mucous.

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