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Copovidone Pharmaceutical Excipients with Many Uses

Copovidone Pharmaceutical Excipients with Many Uses

SUNVIDONE ® VA Synonyms: Copovidone;Copolyvidone; PVP/ VAc CTFA/INCI:VP/VA copolymer CAS No.: [25086-89-9] Trade Name: Sunvidone ® VA SUNVIDONE ® VA is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohols. It is used in the pharmaceutical industry as binders,...

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    SUNVIDONE® VA


    Synonyms: Copovidone;Copolyvidone; PVP/ VAc

    CTFA/INCI:VP/VA copolymer

    CAS No.: [25086-89-9]

    Trade Name: Sunvidone® VA

    SUNVIDONE® VA is a vinylpyrrolidone-vinyl acetate copolymer that is soluble both in water and in alcohols.

    It is used in the pharmaceutical industry as binders, granulating agents, retarding agents and film.

    forming agents in drugs.


    SPECIFICATION

    SUNVIDONE® VA meets the requirements of the latest USP/NF, Ph.Eur. and JPE

    Appearance of solution (10%)

    BY5, B5 min.

    Heavy metals

    20ppm max

    Aldehydes

    500ppm max.

    Loss on drying

    5.0% max

    Peroxides

    400ppm max.

    sulphated ash

    0.1% max

    Hydrazine

    1ppm max.

    K value

    25.2-30.8

    Monomers

    0.1% max.

    Ethenyl acetate

    35.3%-42.0%

    Impurity A

    0.5% max.

    Nitrogen

    7.0%-8.0%


    CHARACTERISTICS

    White or slightly yellowish, free-flowing powder with a faint characteristic odor and practically no taste.

    Sunvidone® VA readily dissolves in all hydrophilic solvents. Solutions of more than 10% concentration can be prepared in: water; ethanol; isopropanol; methylene chloride; glycerol; propylene glycol; It is less soluble in: ether; cyclic, aliphatic and alicyclic hydrocarbons.


    APPLICATIONS

    • Binder for tablets and granules

    Dry binder for direct compression

    Wet granulation

    Sunvidone® VA is an excellent binder for tablets and granules.

    Between 2% and 5%, as a proportion of the final weight of the

    preparation, is usually used.

    • Film-coating

    Sunvidone® VA forms films that are soluble at all pH values.

    • Subcoating

    Sunvidone® VA is used in sugar-coating to improve the

    • Sugar-coating

    adhesion of the coating to the surface of the tablet core and to

    • Sprays

    increase the capacity of the coating solution for pigments and

    • Controlled-release preparations

    improve their dispersibility.


    PACKAGES                                      20KG or 25KG net in fiber drum or PP drum

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    If you're looking for copovidone pharmaceutical excipients with many uses, please be free to place orders with our factory. We also support customized production for the famous brands' products. And if you need, the free sample is also available for quality checking.

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